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专利名称：METHODS FOR DNA-DEPENDENT
TARGETING OF A CELL PERMEANTANTIBODY
发明人：Richard H. Weisbart,Robert N. Nishimura申请号：US15047575申请日：20160218
公开号：US20160235859A1公开日：20160818
摘要：The invention provides methods for selective targeting of live cells, which haveundergone or are undergoing radiation or chemotherapy, at a site of interest with a cell-penetrating polypeptide. In one embodiment of the invention, the method comprisescontacting the live cells with a cell-penetrating polypeptide comprising cell-penetratingdeterminants so that the cell-penetrating polypeptide binds extracellular DNA near oraround the live cells so as to form a complex or association therewith such that thecomplex or associated polypeptide-DNA so bound bind the live cells and penetrates thelive cells thereby selectively targeting live cells at a site of interest with a cell-penetrating polypeptide.
申请人：The United States of America as represented by the Department of VeteransAffairs
地址：Washington D.C. DC US
国籍：US
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